Bisoprolol Impurities
Bisoprolol is a cardioselective β1-adrenergic blocking agent used to treat high blood pressure. Bisoprolol can be useful in patients with chronic obstructive pulmonary disease (COPD) due to its receptor selectivity. Bisoprolol Impurities are primarily used as a reference standard in the pharmaceutical industry for analytical method development and validation to detect and quantify trace levels of this potential contaminant during the manufacturing process of the Bisoprolol. It can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Bisoprolol.
Created: 7/31/2025
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 | Impurity Name: Bisoprolol Impurity A IUPAC Name: (2RS)-1-(4-hydroxymethyl-phenoxy)-3- isopropylaminopropan-2-ol CAS Number: 62572-93-4 Molecular Formula: C13H21NO3 Molecular Weight: 293.30 Status: available |
 | Impurity Name: Bisoprolol Impurity B IUPAC Name: (2RS)-1-Isopropylamino-3-[4-(2-propoxy-ethoxymethyl)phenoxy]propan-2-ol CAS Number: 1447715-44-7 Molecular Formula: C18H31NO4 Molecular Weight: 325.40 Status: available |
 | Impurity Name: Bisoprolol Impurity C IUPAC Name: 1-[4-[4-(2-Hydroxy-3-isopropylaminopropoxy)benzyl]phenoxy]-3-isopropylaminopropan-2-ol CAS Number: 1797132-90-1 Molecular Formula: C25H38N2O4 Molecular Weight: 430.60 Status: available |
 | Impurity Name: Bisoprolol Impurity D IUPAC Name: 1-[4-[4-(2-Hydroxy-3-isopropylaminopropoxy)benzyloxylmethyl]phenoxy]-3-isopropylaminopropan-2-ol CAS Number: 1225195-71-0 Molecular Formula: C26H40N2O5 Molecular Weight: 460.60 Status: available |
 | Impurity Name: Bisoprolol Impurity E IUPAC Name: (EZ)-[3-[4-(2-isopropoxy-ethoxymethyl)phenoxy]allyl]isopropylamine CAS Number: 1217245-60-7 Molecular Formula: C18H29NO3 Molecular Weight: 307.40 Status: available |
 | Impurity Name: Bisoprolol Impurity F IUPAC Name: (2RS)-2-[4-(2-isopropoxy-ethoxymethyl)phenoxy]-3-isopropylaminopropan-2-ol CAS Number: 1798418-82-2 Molecular Formula: C18H31NO4 Molecular Weight: 325.40 Status: available |
 | Impurity Name: Bisoprolol Impurity G IUPAC Name: (2RS)-1-[4-[[(2-isopropoxyethoxy)methoxy]methyl]phenoxy]-3-isopropylaminopropan-2-ol CAS Number: 1215342-36-1 Molecular Formula: C19H33NO5 Molecular Weight: 355.40 Status: available |
 | Impurity Name: Bisoprolol Impurity J IUPAC Name: (2RS)-3-[4-((2-Isopropoxyethoxy)methyl)phenoxy]-1,2-propanediol CAS Number: 1797024-50-0 Molecular Formula: C15H24O5 Molecular Weight: 284.40 Status: available |
 | Impurity Name: Bisoprolol Impurity K IUPAC Name: 2-Isopropoxyethyl 4-[[(2RS)-2-hydroxy-3-(isopropylamino)propyl]oxy]benzoate CAS Number: 864544-37-6 Molecular Formula: C18H29NO5 Molecular Weight: 339.40 Status: available |
 | Impurity Name: Bisoprolol Impurity L IUPAC Name: 4-[[(2RS)-2-hydroxy-3-(isopropylamino)propyl]oxy]benzaldehyde CAS Number: 29122-74-5 Molecular Formula: C13H19NO3 Molecular Weight: 237.30 Status: available |
 | Impurity Name: Bisoprolol Impurity U IUPAC Name: 5-[[4-(Hydroxymethyl)phenoxy]methyl]-3-isopropyl-1,3-oxazolidin-2-one CAS Number: 1071765-44-0 Molecular Formula: C14H19NO4 Molecular Weight: 265.30 Status: available |
 | Impurity Name: Bisoprolol Impurity M IUPAC Name: 4-[(2-Isopropoxyethoxy)methyl]phenol CAS Number: 177034-57-0 Molecular Formula: C12H18O3 Molecular Weight: 210.30 Status: available |
 | Impurity Name: Bisoprolol Impurity N IUPAC Name: (2RS)-1-[4-[(2-ethoxyethoxy)methyl]phenoxy]-3-isopropylaminopropan-2-ol CAS Number: 1346601-75-9 Molecular Formula: C17H29NO4 Molecular Weight: 311.40 Status: available |
 | Impurity Name: Bisoprolol Impurity Q IUPAC Name: (2RS)-1-(isopropylamino)-3-[4-(2-methoxyethoxy)methyl]phenoxypropan-2-ol CAS Number: 1346604-00-9 Molecular Formula: C16H27NO4 Molecular Weight: 297.40 Status: available |
 | Impurity Name: Bisoprolol Impurity R IUPAC Name: (2RS)-1-(isopropylamino)-3-(4-methylphenoxy)propan-2-ol CAS Number: 5790-46-5 Molecular Formula: C13H21NO2 Molecular Weight: 223.30 Status: available |
 | Impurity Name: Bisoprolol Impurity S IUPAC Name: 4-Hydroxybenzaldehyde CAS Number: 123-08-0 Molecular Formula: C7H6O2 Molecular Weight: 122.10 Status: available |
 | Impurity Name: Bisoprolol Impurity T IUPAC Name: 4-[(3-Isopropyl-2-oxo-1,3-oxazolidin-5-yl)methoxy]benzaldehyde CAS Number: 1173203-26-3 Molecular Formula: C14H17NO4 Molecular Weight: 263.30 Status: available |